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Koupit kvalitní oxykodonový prášek online

(Hodnocení: 105)

Price range: 220.00€ through 10,600.00€

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Popis

Kupte si kvalitní oxykodonový prášek online.

Oxykodon je polosyntetický opioidní alkaloid podobný morfinu s analgetickým účinkem. Oxykodon uplatňuje svůj analgetický účinek vazbou na mu-receptory v centrálním nervovém systému (CNS), čímž napodobuje účinky endogenních opioidů. Vazba opiátového receptoru stimuluje výměnu GTP za PDB v G-proteinovém komplexu a inhibuje adenylátcyklázu, čímž zabraňuje tvorbě cAMP. Dále je inhibováno uvolňování nociceptivních neurotransmiterů, jako je substance P, kyselina gama-aminomáselná (GABA), dopamin, acetylcholin a noradrenalin. Oxykodon rovněž inhibuje uvolňování vazopresinu, somatostatinu, inzulinu a glukagonu. Kromě toho oxykodon uzavírá napěťově řízené vápníkové kanály typu N a otevírá draslíkové kanály vázané na G-protein, vnitřně opravuje draslíkové kanály, což vede k hyperpolarizaci a snížení nervové excitability.

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Recenze (105)

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Přidat recenzi
Doprava a doručení

 

Discreet Delivery & Total Confidentiality

At Stonersmeds, your privacy is our priority. Every package is shipped in plain, unbranded packaging—no logos, no hints, no worries. Whether it's your front door or a pickup location, your order arrives with complete discretion.

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