Lidocaine Powder CAS 73-78-9

Buy Cheap lidocaine powder At Low Price,Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type.^[11] It is also used to treat ventricular tachycardia e ventricular fibrillation.^[8][9] When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours.^[9][10] Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area.^[11][9] It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.^[9]

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If injected intravenously, it may cause cerebral effects such as confusion, changes in vision, numbness, tingling, and vomiting.^[11][8] It can cause low blood pressure and an irregular heart rate.^[8] There are concerns that injecting it into a joint can cause problems with the cartilage.^[9] It appears to be generally safe for use in pregnancy.^[8] A lower dose may be required in those with liver problems.^[8] It is generally safe to use in those allergic to tetracaine or benzocaine.^[9] Lidocaine is an antiarrhythmic medication of the class Ib type.^[8] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart.^[11][8] When injected near nerves, the nerves cannot conduct signals to or from the brain.^[9]

Lidocaine was discovered in 1946 and went on sale in 1948.^[12] It is on the World Health Organization’s List of Essential Medicines.^[13] It is available as a generic medication.^[9][14] In 2023, it was the 277th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.^[15][16]

The efficacy profile of lidocaine as a local anaesthetic is characterized by a rapid onset of action and intermediate duration of efficacy.^[11] Therefore, lidocaine is suitable for infiltration, block, and surface anaesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for spinal and epidural anaesthesias; lidocaine, though, has the advantage of a rapid onset of action.^[11]

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Lidocaine is one of the most commonly used local anaesthetics in dentistry. It can be administered in multiple ways, most often as a nerve block or infiltration, depending on the type of treatment carried out and the area of the mouth worked on.^[11]

For surface anaesthesia, several formulations can be used for endoscopies, before intubations. Lidocaine drops can be used on the eyes for short ophthalmic procedures. There is tentative evidence for topical lidocaine for neuropathic pain e skin graft donor site pain.^[11][17][18] As a local numbing agent, it is used for the treatment of premature ejaculation.^[19]

An adhesive transdermal patch containing a 5% concentration of lidocaine in a hydrogel bandage, is approved by the US FDA for reducing nerve pain caused by shingles.^[20] The transdermal patch is also used for pain from other causes, such as compressed nerves and persistent nerve pain after some surgeries.

Lidocaine is a common class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, o cardiac catheterization) if amiodarone is not available or contraindicated.^[11] Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine preventive dose is no longer recommended after a myocardial infarction as the overall benefit is not convincing.^[21]

A 2013 review on treatment for neonatal seizures recommended intravenous lidocaine as a second-line treatment, if phenobarbital fails to stop seizures.^[22]

Intravenous lidocaine infusions are also used to treat chronic pain e acute surgical pain as an opiate sparing technique. The quality of evidence for this use is poor so it is difficult to compare it to placebo or an epidural.^[23]

Inhaled lidocaine can be used as a cough suppressor acting peripherally to reduce the cough reflex. This application can be implemented as a safety and comfort measure for people needing intubation, as it reduces the incidence of coughing and any tracheal damage it might cause when emerging from anaesthesia.^[24]

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A 2019 systematic review of the literature found that intraurethral lidocaine reduces pain in men who undergo cystoscopic procedures.^[25]

Lidocaine, along with ethanol, ammonia, e acetic acid, may also help in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.^[26][27]

For gastritis, drinking a viscous lidocaine formulation may help with the pain.^[28]

A 2021 study found that lidocaine 5% spray on glans penis 10-20 minutes prior to sexual intercourse significantly improves premature ejaculation.^[29] Another study found that lidocaine-prilocaine cream 5% is effective in premature ejaculation and 20 minutes of application time before sexual intercourse.^[30]

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Descrizione del prodotto: Lidocaine is a widely used local anesthetic and antiarrhythmic drug. It works by blocking nerve signals in the body, making it essential for pain management and surgical procedures. Lidocaine is also used in various medical applications to treat conditions involving pain and heart rhythm disturbances. Its effectiveness in numbing specific areas makes it invaluable in both dental and minor surgical procedures.

Manufacturing Excellence: Our Lidocaine is produced under strict GMP (Good Manufacturing Practice) conditions to ensure the highest levels of purity and safety. Each batch undergoes rigorous testing to meet and exceed regulatory standards, ensuring its efficacy and consistency for medical use.

Applications: Lidocaine is primarily used as a local anesthetic in dental procedures, minor surgeries, and other medical settings where pain management is necessary. It is also employed as an antiarrhythmic agent in emergency medical scenarios to manage heart rhythm disorders.

Packaging: Lidocaine is packaged with special attention to maintaining its chemical stability and ensuring long-term efficacy. Our packaging is designed to protect the product from moisture, heat, and contamination.

Shipping & Handling: We utilize advanced shipping solutions to deliver Lidocaine securely and efficiently. Our handling procedures are optimized to ensure the product maintains its integrity and quality from our facility to the end user.

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