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Kup wysokiej jakości proszek oksykodonu online

(105 opinii klienta)

Price range: 220.00€ through 10,600.00€

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Opis

Kupić jakość Oxycodone proszku online.

Oksykodon jest półsyntetycznym morfinopodobnym alkaloidem opioidowym o działaniu przeciwbólowym. Oksykodon wywiera swoje działanie przeciwbólowe poprzez wiązanie się z receptorami mu w ośrodkowym układzie nerwowym (OUN), naśladując w ten sposób działanie endogennych opioidów. Wiązanie receptora opiatowego stymuluje wymianę GTP na PDB w kompleksie białka G i hamuje cyklazę adenylanową, zapobiegając w ten sposób wytwarzaniu cAMP. Ponadto hamowane jest uwalnianie neuroprzekaźników nocyceptywnych, takich jak substancja P, kwas gamma-aminomasłowy (GABA), dopamina, acetylocholina i noradrenalina. Oksykodon hamuje również uwalnianie wazopresyny, somatostatyny, insuliny i glukagonu. Ponadto oksykodon zamyka bramkowane napięciem kanały wapniowe typu N i otwiera związane z białkiem G kanały potasowe, wewnętrznie naprawiając kanały potasowe, co powoduje hiperpolaryzację i zmniejszenie pobudliwości neuronów.

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Recenzje (105)

105 opinii dla Buy Quality Oxycodone powder online

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Wysyłka i Dostawa

 

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